Halfway as a result of his profession, Cees Dekker reinvented himself. Just after several years of hardcore physics, he shifted his aim to ‘nanobiology’ with the turn on the millennium. A term he coined himself, being a matter of simple fact.
But how do morality, the dignity of the individual, my expertise from the this means of daily life, stick to in the motion of atoms? A purely naturalistic point of view fails listed here; a Christian perspective, I feel, is a much more fair strategy to interpret these elements of truth.’
, Groningen researchers current the final results in their initiatives to help make labs more sustainable and supply tips for other labs.
Considering that 2000, Dekker has shifted the most crucial concentrate of his do the job in the direction of biophysics the place he studies the Qualities of solitary biomolecules and cells utilizing the applications of nanotechnology. This change of discipline was pushed by his fascination for that remarkable functioning of biological molecular constructions, together with via the long-phrase viewpoint that lots of interesting discoveries may be anticipated In this particular subject.[five] Latest strains of investigate in his biophysics team are in the areas of:[6]
This yielded a breakthrough. In just only a few months, we had been capable to evaluate transportation through a person solitary-walled carbon nanotube. Based upon small-temperature experiments by a brilliant PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft College of Technological know-how using an Lively analysis lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with really extensive (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is always that these factors together make up a living technique. The trick of said existence, I feel, lies during the interactions, the interplay of These molecules. The large problem about the origin of lifestyle continues to be unanswered. How did we ever evolve from basic molecules in the exceptionally complex devices we cees dekker see now? We do not know. I need to operate on These types of significant, open up thoughts.’
Nanopores signify an elegant and flexible Instrument to measure single molecules. We research novel detection modes with solid-state nanopores as well as various ways to evaluate proteins with nanopores. Jobs encompass the subsequent:
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Quite cool, but that wasn’t actually where by my interest lay. I wished to pioneer And that i experienced the feeling that was no more possible, since the most appealing essential insights had by now been uncovered. But my field had designed lots of thrilling new equipment to evaluate unique molecules. I made a decision that I desired to implement this to biology, to have a look at it from the Actual physical point of view.’
Testing pseudotopological and nontopological styles for SMC-pushed DNA loop extrusion in opposition to roadblock-traversal experiments
1999, initially measurement from the wavefunction of solitary molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for any new Luttinger description of interacting electrons in nanotubes
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments